Study of naldemedine for opioid-induced constipation in cancer patients
Part of Cancer, Mental health clinical trials.
This trial tests whether naldemedine, a medication for constipation, can help cancer patients who have constipation caused by opioids. It looks at how well it works and how patients feel.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with cancer
- You take opioids (pain medicine) every day
- You are currently using laxatives (medication for constipation)
- You are having constipation that bothers you
- You can fill out a questionnaire in Dutch
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether naldemedine is safe and how the body processes it in children who take opioid medicines and are dealing with constipation or are at risk for it. It may help some children by reducing constipation side effects from opioid pain treatment.
This trial tests whether starting a laxative right away can prevent constipation caused by pain medications called opioids. It's for people with advanced cancer who are beginning opioid pain treatment and aims to improve comfort and quality of life.
This study looks at how well naldemedine (and certain other constipation medicines) lower the risk of major heart problems in people who take opioids for constipation. It compares medicine use patterns in people with opioid-induced constipation to see who has fewer serious heart events.
This trial tests a new treatment for constipation caused by opioid pain medication. It aims to see if it's safe and effective, and may help you have more regular bowel movements.
This study tests a combination pill (oxycodone with naloxone) that may treat severe cancer pain while also helping with constipation — a common side effect of opioid pain medicines. It is designed for people whose constipation is linked to their painkillers.
This trial studies whether a lidocaine infusion can help manage pain in patients with cancer-related bowel blockages. It aims to see if it can improve pain scores and reduce the need for other pain medications.
Hear when a new Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.