Escitalopram for people with newly diagnosed grade 4 brain tumors
Treatments studied
Part of Cancer clinical trials.
This trial studies whether escitalopram (an antidepressant medication) can help people with grade 4 glioma around the time they start standard cancer treatment. You may be screened especially for depression/anxiety status and medication history, because the study uses a specific mental-health medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of grade 4 glioma (brain tumor) based on biopsy/pathology
- Your glioma is newly diagnosed, and you plan to start chemotherapy and/or radiation
- You can do usual daily activities fairly well (ECOG 0–2 or similar) and are at least 19 years old
- You’re expected to live more than 6 months and you can sign informed consent
- If you’re able to get pregnant: your pregnancy test is negative, and you use effective birth control (or you’re not having periods for 2+ years or have had surgery to prevent pregnancy)
- You can have MRI scans and have no severe kidney problem (GFR less than 30)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a special type of electroacupuncture can help chemotherapy (paclitaxel) reach the brain more effectively in patients whose high-grade glioma has come back after surgery. The goal is to see if this combination can slow tumor growth.
This trial tests whether the diabetes drug sitagliptin (Januvia) can help slow or shrink a recurrent grade 4 glioma (a type of brain tumor). It's for people whose tumor has come back after standard treatment and who have not used sitagliptin or Avastin before.
This trial tests whether adding electroacupuncture (a type of acupuncture with mild electric pulses) to the chemotherapy drug paclitaxel can help people with recurrent high-grade glioma. The goal is to see if the combination works better than paclitaxel alone.
This trial tests a new injection called BC008-1A for people with a grade 4 glioma (a type of brain cancer) that has come back after standard treatment. The goal is to see if the drug can help control the tumor and improve outcomes.
This trial tests whether sitagliptin, a medicine usually used for diabetes, can help people with a fast-growing type of brain tumor (grade 4 glioma). You will take sitagliptin before your planned surgery, and researchers will study how it affects your tumor.
This trial tests whether the antidepressant vortioxetine can help people with newly diagnosed glioblastoma when added to standard radiation and chemotherapy. The goal is to see if it improves mood, quality of life, and possibly treatment outcomes.
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