Clinical trials
Glioma of Brain clinical trials
Below are recruiting glioma of brain clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03684109Recruiting
MRI scans to study brain tumors using molecular imaging
This study uses special MRI scans to better “characterize” (study) gliomas, a type of brain tumor, using information from your brain tissue. You may be eligible if you’re an adult with a suspected or confirmed glioma and you already need a biopsy or surgery.
Miami, FloridaAges 18 years+ - NCT05686798RecruitingPhase 1
Gene therapy plus radiation for recurring brain tumor
This early-phase study tests a “suicide gene” therapy delivered by a virus along with radiation for adults whose high-grade brain tumor has come back or grown again. The goal is to see if the treatment is safe and can help control the tumor.
Detroit, MichiganAges 18 years+ - NCT06640582RecruitingPhase 1/Phase 2
TIL therapy with pembrolizumab for advanced brain cancer
This trial tests a new treatment for advanced brain cancers like glioma and meningioma. It combines your own immune cells (tumor-infiltrating lymphocytes or TILs) with an immunotherapy drug (pembrolizumab) to help your body fight the tumor. It's for people who have tried other treatments without success or have no standard options left.
Beijing, Beijing MunicipalityAges 16–90 - NCT07179328RecruitingPhase 1
Focused ultrasound for glioblastoma during standard chemo
This trial tests whether focused ultrasound can safely open the blood-brain barrier to help your chemotherapy work better. It is for people with glioblastoma who have already completed standard surgery and chemo-radiation and are now on maintenance chemo.
Toronto, OntarioAges 18–85 - NCT07547163Recruiting
Patient feedback on low-grade brain tumor treatment
This study asks patients with a specific type of low-grade brain tumor (IDH mutant grade 2 glioma) to share their experiences and quality of life while receiving a treatment called vorasidenib, with or without radiation. Your feedback helps doctors understand how well the treatment works from your perspective.
MilanAges 18 years+ - NCT06132685RecruitingPhase 2
Dexamethasone dosing after brain tumor surgery
This trial tests how to best use dexamethasone (a steroid) after brain tumor surgery to help recovery and reduce swelling. It looks at different dosing schedules for patients with common brain tumors.
Atlanta, GeorgiaAges 18 years+ - NCT06018363RecruitingPhase 1/Phase 2
Cell therapy for recurrent high-grade glioma
This trial tests a new cell therapy (QH104) for people with an aggressive brain tumor called high-grade glioma that has come back or worsened after standard treatment. The therapy targets a specific protein (B7-H3) on tumor cells to try to fight the cancer.
Suzhou, JiangsuAges 18–70 - NCT05555550RecruitingEarly Phase 1
PET-MRI scan to study low-grade brain tumors in children
This early-phase study tests how well a special PET-MRI scan (using a radioactive tracer) can find and measure low-grade brain tumors. It may help doctors better track these tumors while you start or continue treatment.
Philadelphia, PennsylvaniaAges 1–21 - NCT02619890Recruiting
Brain tumor registry using clinical and brain scan information
This study collects information about people with brain gliomas, including what treatments they receive and what their brain scans show. It’s meant to help researchers better understand these tumors and how they respond to first- or second-line therapy.
SeoulAges 18 years+ - NCT06747728Recruiting
Bevacizumab before surgery for new high-grade brain tumors
This trial tests whether giving bevacizumab (a drug that blocks blood vessel growth) before surgery helps treat newly diagnosed high-grade gliomas. It may be an option for adults who have not had prior anti-angiogenic therapy.
Zhengzhou, HenanAges 18 years+ - NCT07210632RecruitingEarly Phase 1
Nivolumab dye imaging in high grade glioma surgery
This trial tests if a special dye attached to the immunotherapy drug nivolumab can help surgeons see tumor cells during surgery for high grade glioma. You may join if you are scheduled for surgery and your organs are working well.
Nashville, TennesseeAges 18 years+ - NCT07717827Recruiting
Brain tumor surgery guided by brain wiring maps
This trial uses advanced brain scans to create a detailed map of your brain's wiring before surgery. This helps surgeons remove more tumor safely while protecting important areas that control movement, language, and vision.
Palermo, PAAges 18 years+ - NCT02800486RecruitingPhase 2
Targeted antibody plus repeat radiation for recurrent brain tumors
This trial studies giving cetuximab (a targeted antibody) directly into an artery along with repeat radiation to treat certain recurring or treatment-resistant brain tumors. It may help by delivering the drug more directly to tumor areas and testing whether this approach can control the disease after it comes back.
New York, New YorkAges 18 years+ - NCT06753617Enrolling by invitation
Cold probe treatment for brain tumors
This trial tests a cold-based treatment (cryoablation) for certain brain tumors including gliomas, meningiomas, and metastases. It may be an option if you plan to have surgery and meet safety criteria.
Rotterdam, South HollandAges 18–80 - NCT07612917Recruiting
Brain Activity Changes in Glioma Patients During Treatment
This study tracks how brain activity and connections change in patients with gliomas (brain tumors) as they receive treatment. Researchers use special brain scans to understand how treatment affects the brain's function, which may help improve care for glioma patients in the future.
Linz, Upper AustriaAges 18–64 - NCT03728673RecruitingPhase 2
Escitalopram for people with newly diagnosed grade 4 brain tumors
This trial studies whether escitalopram (an antidepressant medication) can help people with grade 4 glioma around the time they start standard cancer treatment. You may be screened especially for depression/anxiety status and medication history, because the study uses a specific mental-health medicine.
Omaha, NebraskaAges 19 years+ - NCT05278715RecruitingPhase 2
New treatment plan for optic pathway glioma in children
This Phase 2 trial tests a modified chemotherapy treatment plan for children and young people with optic pathway glioma, aiming to shrink tumor and improve eye/brain symptoms. You may be able to join if your diagnosis is confirmed and your body can safely handle treatment.
BeijingAges 3 months–21 years - NCT04135807RecruitingEarly Phase 1
Implantable device test for operable brain tumor patients
This early-phase trial tests a tiny implanted device placed during brain tumor surgery. It delivers very small doses of medicine directly to the tumor area for a short time, aiming to see if this approach is safe and workable in patients with certain gliomas.
Boston, MassachusettsAges 18 years+ - NCT07198256Recruiting
AI-assisted diagnosis of brain tumors
This trial tests an AI tool that helps diagnose brain tumors like glioma, brain metastases, and lymphoma using MRI scans. It may allow faster and more accurate diagnosis without needing additional tests.
Hangzhou, ZhejiangAges 18–100 - NCT06016452RecruitingPhase 2
Chlorophyllin for brain radiation damage in glioma patients
This trial tests if chlorophyllin can help manage brain damage caused by radiation therapy in people with diffuse glioma. It may reduce symptoms or prevent them from getting worse.
Mumbai, MaharashtraAges 18–70 - NCT07416188RecruitingPhase 1/Phase 2
LMP744 drug for returning glioblastoma
This trial tests an experimental drug called LMP744 for people whose glioblastoma has come back. It aims to see if the drug can slow or stop tumor growth by targeting specific proteins in cancer cells.
Bethesda, MarylandAges 18–99 - NCT07465796Recruiting
Testing a new device during brain tumor surgery
This trial is testing a new tool called the CIPHER System during brain surgery for people with a newly diagnosed glioma. It looks at how well the tool works and how safe it is when used during the procedure.
Melbourne, VictoriaAges 18–75 - NCT07110246RecruitingPhase 2
Dabrafenib and trametinib for BRAF-mutated low-grade gliomas
This trial tests two targeted drugs (dabrafenib and trametinib) for children and young adults with a specific type of low-grade brain tumor that has a BRAF V600 mutation. The drugs work by blocking signals that help the tumor grow.
Birmingham, AlabamaAges 1–25 - NCT05298995RecruitingPhase 1
GD2 CAR T-cell treatment for pediatric brain tumors
This trial tests a special immune-cell therapy (GD2 CAR T cells) made for pediatric brain tumor patients. It uses a planned treatment plan and monitoring to see if the therapy is safe and can work against the tumor.
Roma, ItalyAges 6 months–30 years
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Common questions
- Are there clinical trials for glioma of brain?
- Yes. Clin2 currently lists 120 recruiting glioma of brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glioma of brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glioma of brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.