Vortioxetine for newly diagnosed glioblastoma
Treatments studied
Part of Cancer clinical trials.
This trial tests whether the antidepressant vortioxetine can help people with newly diagnosed glioblastoma when added to standard radiation and chemotherapy. The goal is to see if it improves mood, quality of life, and possibly treatment outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a newly diagnosed glioblastoma (a type of brain cancer) and will receive the standard radiation plus chemotherapy (temozolomide) after surgery
- Your level of daily function is fairly good — a Karnofsky score of at least 70 (you can care for yourself but might not be able to do heavy activities)
- You are not pregnant, breastfeeding, or planning pregnancy, and if you could have children, you agree to use effective birth control during the trial and for 6 months after
- You have no serious depression, bipolar disorder, schizophrenia, or recent thoughts of suicide or harming others
- You have no other active cancers (unless they have been gone without treatment for at least 1 year)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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