HER2-targeted oncolytic virus plus custom immune cells for solid cancers
Part of Cancer, Digestive system, Kidney & urinary, Lungs & breathing, Mouth & dental, Skin, Women’s health & pregnancy clinical trials.
This Phase 1 study tests a treatment plan that combines a virus designed to attack cancer with your own custom immune cells that target HER2. It aims to shrink advanced HER2-positive solid tumors (and make future options safer/more effective).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced HER2-positive solid cancer confirmed from tumor testing (IHC).
- Your cancer cannot be cured with standard options like surgery, radiation, or chemotherapy (and standard treatments have been tried or are not available).
- Your cancer has gotten worse after first-line treatment, or you have no effective remaining treatment options.
- You have at least one tumor spot that doctors can safely inject directly, and you have scan results showing measurable disease.
- You can likely tolerate treatment: you’re an adult (18+), expected to live more than 12 weeks, and blood organ tests meet required limits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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