Clin2
NCT03756961Possibly a fitRecruiting

Opioid-free care plan for people having weight-loss surgery

ObesityPain, Postoperative

Treatments studied

Part of Hormones & metabolism, Pain clinical trials.

This trial studies whether an opioid-free or opioid-sparing care pathway can improve comfort and outcomes for adults undergoing laparoscopic weight-loss surgery. It may help people avoid side effects from opioid pain medicines while still managing pain safely.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
220 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older and planning weight-loss surgery (laparoscopic gastric bypass or sleeve) at the study hospital.
  • You are well enough medically—for example, you should not have severe overall health risk (ASA higher than 3).
  • You do not have certain heart rhythm or heart conditions (like very slow heart rate under 50 bpm).
  • You can safely take the planned study medicines and have no known allergy to oxycodone, esketamine, dexmedetomidine, or lidocaine.
  • You can speak Swedish well enough and complete questionnaires; you should also not have serious untreated mental or thinking problems.
  • You are not pregnant, and if you could become pregnant, you must use reliable birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07568938Recruiting
Anesthesia types and stress response in weight-loss surgery

This study compares two anesthesia methods—inhaled gas (desflurane) versus IV medication (TIVA)—during weight-loss surgery to see how each affects your body's stress response and recovery. The goal is to understand which approach may be safer and more comfortable for patients having bariatric surgery.

Athens
NCT07105839Not yet recruiting· Phase 4
Comparing anesthesia with and without opioids for weight-loss surgery

This study compares two ways of providing anesthesia during weight-loss surgery: one that uses opioid painkillers and one that does not. The goal is to see if avoiding opioids leads to better recovery and fewer complications after surgery.

NCT06738043Not yet recruiting
Pain relief options for weight-loss surgery

This study compares two medicines, dexmedetomidine and ketamine, added to standard anesthesia to see which one provides better pain control during and after weight-loss surgery. It aims to improve recovery and comfort for patients.

NCT06915558Recruiting
Reducing inflammation in weight loss surgery

This trial tests a method to control inflammation during bariatric surgery. It may help patients recover better and have fewer complications.

Barcelona, Barcelona
NCT06650371Not yet recruiting
Anesthesia without opioids for weight-loss surgery

This study compares two types of anesthesia for weight-loss surgery: one that uses standard painkillers (opioids) and one that avoids these drugs. The goal is to see which approach works better for recovery and pain control.

NCT07084753Not yet recruiting
Pain control without opioids for weight-loss surgery

This study compares two ways to manage pain during and after your weight-loss surgery: one uses a nerve block (thoracic paravertebral block) to numb the area without opioid painkillers, and the other uses standard anesthesia. The goal is to see if the nerve block method reduces pain and improves recovery without the side effects of opioids.

Zagreb, City of Zagreb

Hear when a new Obesity trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.