Study of linvoseltamab for hard-to-treat multiple myeloma
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests linvoseltamab, an experimental antibody medicine, in adults whose multiple myeloma has come back or does not respond to treatment. It may help some people by targeting myeloma cells after multiple prior therapies have failed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have active multiple myeloma confirmed by standard blood/bone marrow criteria
- Your overall health is good enough for treatment (ECOG 0–1)
- Your myeloma must still be measurable for response (your team can track if it’s improving or worsening)
- Your myeloma has progressed after several prior treatments (at least 3 lines, or is “triple-refractory” to key drug types)
- You either cannot tolerate or have not responded within about 60 days of finishing key treatments like proteasome inhibitors, IMiDs, and an anti-CD38 antibody
- You do not have certain excluded conditions, like plasma cell leukemia, POEMS, or primary light-chain amyloidosis; and you can’t have myeloma in the brain/meninges
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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