Linvoseltamab combo for hard-to-treat multiple myeloma
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests a new drug called linvoseltamab combined with other cancer treatments for people with multiple myeloma that has stopped responding to standard therapies. It may be an option if you have already tried several treatments and are looking for a new approach.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have multiple myeloma that has come back or stopped responding to at least 3 previous treatments (or to 2 treatments if you've already taken certain drugs).
- You are generally well enough to do light work or housework (ECOG performance status 0 or 1).
- Your kidney, liver, and blood cell counts are working well enough, as determined by your doctor.
- You have not had certain types of immunotherapy (like CAR T or bispecific antibodies) that target a protein called BCMA on your myeloma cells.
- You do not have a history of certain other conditions like plasma cell leukemia or amyloidosis.
- You are willing to be treated at a study center and follow the study schedule.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests linvoseltamab (a new targeted immune treatment) to see if it’s safe and how well it works in adults with recently diagnosed multiple myeloma who haven’t started treatment yet. Because it’s a “window of opportunity” study, it’s meant to learn early results before standard therapy is fully underway.
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This trial compares a new drug called linvoseltamab to standard treatments for multiple myeloma. It is for people who cannot have a stem cell transplant and have not had extensive prior therapy.
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