Testing imaging tools to assess a narrowed left main artery
Part of Heart & circulation clinical trials.
This trial compares different heart scans to decide how serious a narrowing is in the left main coronary artery. It may help doctors choose the safest and most accurate way to manage that blockage during a heart catheter procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older.
- You have a narrowing in the left main artery (LM) that looks moderate (about 30% to 80% narrowed) on angiogram, or the angiogram is unclear.
- You have no major additional blockages in the left front (LAD) or left side (LCX) arteries beyond what’s allowed (with some limited exceptions like certain branch or artery openings).
- You have not had certain prior heart procedures for the left coronary system (no prior stent in the left system, no bypass surgery).
- You can safely take the study medicines and contrast used during the procedure (no allergy/contraindication to heparin, iodine contrast, beta-blocker, nitroglycerin, or adenosine), and your kidneys are healthy enough for contrast.
- You are able to provide consent and do not have pregnancy risk rules that can’t be met, and you’re not expected to have less than 1 year of life expectancy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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