Clin2
NCT03853733Possibly a fitRecruiting

Shorter radiation plan for non-surgery rectal cancer

Rectal Cancer

Part of Cancer, Digestive system clinical trials.

This trial looks at a shorter radiation schedule for people with advanced rectal (or nearby sigmoid) cancer who cannot have surgery. The goal is to control the cancer while keeping treatment simpler, especially for those who cannot safely undergo an operation.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You have rectal or sigmoid (near-rectum) cancer
  • Surgery is not an option for you due to age, other illnesses, or multiple cancers in other organs
  • You are at least 18 years old
  • Your radiation plan matches 39 Gy given in 13 sessions (3 Gy per session)
  • You are not receiving chemotherapy at the same time as the radiation
  • After radiation, you still are not expected to be able to have surgery

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03466424Recruiting
Short radiation then chemotherapy for locally advanced rectal cancer

This trial tests a short course of radiation given before chemotherapy for people with locally advanced rectal cancer (cancer that has grown into nearby tissue and/or nearby lymph nodes but can still be removed). It may help shrink the tumor and make treatment more effective while assessing how well this approach works.

Fuzhou, Fujian
NCT06729645Not yet recruiting
Radiation therapy for rectal cancer in older adults

This trial studies a special type of radiation therapy for older adults with rectal cancer who are not able or willing to have surgery. It combines external beam radiation with a short, focused radiation treatment inside the rectum (brachytherapy) to try to control the cancer while avoiding the risks of surgery.

Kempten, BaBaden-Württembergs
NCT06652412Not yet recruiting· Phase 2
Shorter radiation with medication for older adults with colorectal cancer

This trial tests a shorter course of radiation therapy combined with medication for older or frail patients with colorectal cancer that cannot be removed by surgery. The goal is to control the cancer while reducing side effects and improving quality of life.

NCT06958432Recruiting· Phase 2/Phase 3
Shorter radiation before chemo and immunotherapy for rectal cancer

This trial tests a shorter course of radiation before chemotherapy and an immunotherapy drug to shrink mid-to-lower rectal cancer that has not spread. The goal is to improve treatment response and reduce side effects, potentially allowing for less invasive surgery.

Guangzhou, Guangdong
NCT07068763Recruiting· Phase 2
Short radiation plus drugs for early rectal cancer

This trial tests a combination of short-course radiation, chemotherapy (capecitabine), and two immunotherapy drugs (PD-1 and CTLA-4 inhibitors) for people with early-stage rectal cancer who want to avoid surgery and keep their anus. The goal is to see if this treatment can shrink the tumor enough to avoid major surgery.

Hangzhou, Zhejiang
NCT06162650Recruiting· Phase 2
Pre-surgery chemo-radiation therapy for rectal cancer

This trial tests a combination of chemotherapy and radiation therapy before surgery for people with mid or low rectal cancer that hasn't spread. The goal is to see if this approach works better than current treatments.

Tainan

Hear when a new Rectal Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.