Study immune-cell changes after a controlled endotoxin exposure
Part of Lungs & breathing clinical trials.
This study tests how your lungs’ immune cells respond after a controlled exposure to endotoxin. It may help researchers understand and prevent harmful lung inflammation, even though it is a short, research-focused intervention.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are willing and able to sign a written consent form
- You are between 18 and 50 years old
- You have not had a current or recent illness in the past 2 weeks
- You do not have known heart, lung, or major body-wide (systemic) diseases
- You are not on medicines that can increase bleeding, like blood thinners or antiplatelet drugs
- Your screening breathing test (spirometry) and heart tracing (ECG) are normal
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies how immune cells in the lungs and gut microbes (your microbiome) change during ARDS and how these changes relate to your outcomes. It may help researchers better predict and treat ARDS by learning what’s going on in the lungs and body systems.
This study tests how the nose reacts to a substance that causes mild inflammation in people with asthma. It may help understand airway inflammation and asthma better.
This trial studies whether changing immune cells in the lungs (using a procedure called MiniBAL) can improve outcomes in adults who are critically ill and on a breathing tube. It may help doctors better manage acute lung injury by targeting inflammation early in the ICU stay.
This trial tests how putting a small amount of endotoxin into a specific part of the lung affects the body. It’s designed for healthy, nonsmoking adults, and may help researchers understand lung and immune responses.
This study checks how your immune system (your body’s defense system) reacts to a controlled substance that triggers inflammation. It may help researchers understand why some people have stronger or weaker inflammatory responses.
This study looks at how the immune system works and how well diseases like asthma, COPD, and others are controlled. You may join if you have one of these conditions or if you are a healthy volunteer or smoker without lung disease.
Hear when a new ARDS, Human trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.