Breathing tube patients in ICU tested for lung inflammation treatment
Part of Infections, Lungs & breathing clinical trials.
This trial studies whether changing immune cells in the lungs (using a procedure called MiniBAL) can improve outcomes in adults who are critically ill and on a breathing tube. It may help doctors better manage acute lung injury by targeting inflammation early in the ICU stay.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be an adult age 18 or older and be in an intensive care unit (ICU)
- Have a breathing tube in your mouth or nose, or expect to get one within 48 hours
- Be able to give consent (or have your legal decision-maker consent if you can’t) before any study steps
- You should not have had an organ transplant or a bone marrow transplant
- You should not be at high risk of bleeding (for example, very high INR or PTT on labs)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at how a type of white blood cell affects lung inflammation in people with severe influenza. It may help researchers find better treatments for respiratory failure caused by the flu or other infections.
This trial tests a new way to adjust breathing machine settings for people with a lung condition called ARDS. The adjustments are based on detailed monitoring of the heart and lungs, aiming to improve recovery.
This trial tests whether using non-invasive suctioning methods (without needing to disconnect the breathing tube) can lower the risk of lung infections in critically ill patients who need a breathing tube. It may help reduce the chance of pneumonia during intensive care.
This study tests whether giving inhaled antibiotics based on a patient's own airway bacteria can prevent ventilator-associated pneumonia (a lung infection from the breathing tube) in intensive care patients. It may help reduce infections in people who need a breathing tube for more than three days.
This trial studies how immune cells in the lungs and gut microbes (your microbiome) change during ARDS and how these changes relate to your outcomes. It may help researchers better predict and treat ARDS by learning what’s going on in the lungs and body systems.
This study looks at different types of lung infections in ICU patients on breathing machines. By analyzing fluid from your lungs, researchers hope to better understand pneumonia and improve treatment.
Hear when a new Acute Respiratory Distress Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.