Study drug-free lung irritation using endotoxin in healthy adults
Treatments studied
Part of Lungs & breathing clinical trials.
This trial tests how putting a small amount of endotoxin into a specific part of the lung affects the body. It’s designed for healthy, nonsmoking adults, and may help researchers understand lung and immune responses.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 to 45 years old
- You must be generally healthy, with no major ongoing medical conditions (heart, lung, brain/seizures, kidney, autoimmune/rheumatologic, hormone, liver, gut, or infections like HIV)
- You should not be pregnant or breastfeeding
- Your BMI must be 30 or less
- You must avoid certain medicines (including aspirin and anti-inflammatory drugs) for at least 7 days before joining
- If you’ve smoked before, you must have quit for at least 1 year (and have limited total smoking history); no frequent vaping/hookah more than once a week in the last 6 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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