Preventing an abnormal heart rhythm after heart surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial studies whether giving a medication (amiodarone) during and after certain heart surgeries can help prevent atrial fibrillation, an irregular heartbeat that can happen after surgery. It may help by aiming to stop this rhythm problem before it starts.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for your first, planned (not emergency) open-heart surgery (like CABG or valve repair/replacement, or combined procedures).
- Before surgery, your heart rhythm is normal sinus rhythm (your heart is in a regular rhythm).
- You do not have a known history of atrial fibrillation (and no known episodes of related fast/irregular rhythms lasting more than 30 seconds).
- You have not had a previous heart surgery that used a heart-lung bypass machine (cardiopulmonary bypass).
- You have never been treated with amiodarone for an abnormal fast rhythm coming from the upper heart chambers.
- You are not going to need a surgery specifically to treat rhythm problems in the atria (like pulmonary vein isolation or a Maze procedure).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether using radiofrequency energy to isolate a small area in the heart's left upper chamber can prevent a common irregular heartbeat (atrial fibrillation) after heart surgery.
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
This trial tests whether a medicine called amiodarone can help prevent an irregular heartbeat (atrial fibrillation) that sometimes happens after heart surgery. If you are having heart surgery (other than bypass surgery) and have a normal heart rhythm, this study might help you recover with fewer heart rhythm problems.
This study tests whether giving a short course of a medication called amiodarone after heart surgery helps prevent or control new irregular heartbeats (atrial fibrillation) and helps you leave the hospital sooner.
This trial tests if placing a small amount of amiodarone medicine near the heart during open-chest surgery can help prevent a common irregular heartbeat (atrial fibrillation) that often happens after heart surgery.
This trial tests a biodegradable patch that slowly releases amiodarone directly onto the heart during surgery. It aims to prevent atrial fibrillation, a common irregular heartbeat after heart surgery.
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