Amiodarone to prevent atrial fibrillation after heart surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if giving the medication amiodarone before and after heart surgery can prevent a common complication called atrial fibrillation (an irregular heartbeat). It is for people who do not already have atrial fibrillation and are having heart surgery that is not coronary artery bypass.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are having heart surgery other than coronary artery bypass (like valve repair or replacement).
- You have a normal heart rhythm before surgery (no atrial fibrillation or flutter).
- You do not have certain heart conditions like heart block or sick sinus syndrome.
- You have not used amiodarone before surgery.
- You do not have liver, thyroid, or lung problems that make amiodarone unsafe.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if placing a small amount of amiodarone medicine near the heart during open-chest surgery can help prevent a common irregular heartbeat (atrial fibrillation) that often happens after heart surgery.
This trial tests whether adding minocycline to amiodarone (or using amiodarone alone) can prevent atrial fibrillation after heart surgery. If you’re at risk for this irregular heartbeat after surgery, the study may help find a safer or more effective way to lower that risk.
This trial compares two medicines—vernakalant and amiodarone—to see which works better to treat atrial fibrillation after heart surgery. It may help you (or your relative) stay in a steadier heart rhythm during recovery.
This trial tests if amiodarone, a medication that helps keep your heart rhythm steady, can prevent a type of irregular heartbeat called atrial fibrillation after surgery to remove part of your esophagus. If you are having this surgery (called minimally invasive esophagectomy or MIE) for cancer or other esophagus problems, you may be able to join.
This trial looks at whether a special heart rhythm treatment called “ablation” works well when done during certain heart operations. It may help reduce atrial fibrillation (AF) symptoms or future abnormal rhythm episodes for people who are already having surgery.
This trial tests whether taking a heart rhythm medication after a minimally invasive aortic valve procedure (TAVR) can prevent irregular heartbeats that sometimes develop after the surgery. You may qualify if you're having TAVR for a narrowed aortic valve and show signs of extra heartbeats in the first 24 hours after the procedure.
Hear when a new Atrial fibrillation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.