Amiodarone patch to prevent afib after heart surgery
Part of Heart & circulation clinical trials.
This trial tests a biodegradable patch that slowly releases amiodarone directly onto the heart during surgery. It aims to prevent atrial fibrillation, a common irregular heartbeat after heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for elective (non-emergency) heart surgery through a full breastbone incision.
- Your surgery is for blocked heart arteries, or a diseased aortic, mitral, or tricuspid valve, or an enlarged ascending aorta, or a combination of these.
- You have never had atrial fibrillation or any other abnormal heart rhythm problem (arrhythmia).
- This is not a repeat heart surgery – you haven't had heart surgery before.
- Your surgery is not an emergency for a heart attack or shock, and you do not have thyroid problems, hypertrophic cardiomyopathy, a pacemaker, or an ICD (implantable defibrillator).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing whether giving amiodarone (a heart-rhythm medicine) before an electrical cardioversion can help restore normal heart rhythm better in people with persistent atrial fibrillation. The goal is to see if the medicine makes the procedure more likely to succeed and reduces the chance of the irregular rhythm returning.
This trial tests a remote heart monitoring patch to see if it can safely and effectively track your heart rhythm after a procedure called catheter ablation for atrial fibrillation. It could help your doctor keep an eye on your recovery without extra clinic visits.
This study tests a modified 'pills-in-the-pocket' approach—taking antiarrhythmic drugs only when symptoms occur—for people with non-valvular atrial fibrillation (AF) who still have arrhythmias lasting over 24 hours after their first catheter ablation. It aims to see if this strategy can safely control symptoms without needing daily medication.
This trial tests a patch that releases amiodarone, a medicine that helps prevent a common irregular heartbeat after open-heart surgery. The patch is placed on the heart during surgery to stop new atrial fibrillation from starting.
This trial tests if giving the medication amiodarone before and after heart surgery can prevent a common complication called atrial fibrillation (an irregular heartbeat). It is for people who do not already have atrial fibrillation and are having heart surgery that is not coronary artery bypass.
This trial studies whether a short course of amiodarone started right after heart surgery can reduce problems from new-onset atrial fibrillation (a common fast heart rhythm) or flutter. It may help some patients avoid ongoing rhythm issues and improve recovery soon after discharge.
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