Folfiri plus cetuximab for advanced, gene-matched colon cancer
Part of Cancer, Digestive system clinical trials.
This trial tests whether a combination chemotherapy (Folfiri) plus cetuximab works better for people with stage IV colorectal cancer that has specific tumor gene markers and a specific blood-gene type. It may help you shrink tumors or control the cancer if you match the study’s required lab and health criteria.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of colorectal adenocarcinoma (colon/rectal cancer).
- Your tumor test shows KRAS, NRAS, and BRAF are wild-type (not the “mutated” forms the study excludes).
- Your genetic blood type is FcγRIIIa V/V (a specific variant found on blood-genetic testing).
- Your cancer is stage IV and you have at least one measurable tumor spot on scans.
- Your overall health score is ECOG 0 or 1, and you are expected to live more than 3 months.
- Your bloodwork and organ tests are within required limits (white blood cells, platelets, hemoglobin, kidney, and liver/bilirubin).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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