Compare faster versus standard corneal strengthening
Part of Eyes & vision clinical trials.
This trial compares two ways to strengthen the cornea (the clear front surface of your eye) in people with keratoconus or corneal weakening after laser vision surgery. It may help determine whether an accelerated (faster) approach works as well and with acceptable safety.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have keratoconus, or corneal thinning/weakening after refractive (vision) surgery
- Your cornea is thick enough for the procedure
- You do not have eye problems that raise the risk of complications
- You have no past chemical eye injury or slow healing of the eye surface
- You are not pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a lab-grown (ex vivo) method of strengthening donor cornea tissue used in cornea transplants for people with keratoconus. It may help improve how well the transplanted cornea heals and functions.
This study tests a same-day procedure that strengthens the cornea (the clear front part of the eye) in both eyes using a special light treatment, called cross-linking. It may help slow or stop the progression of keratoconus, a condition where the cornea becomes cone-shaped and causes blurry vision.
This trial tests two different laser-based procedures to treat keratoconus, a condition that weakens and bulges the cornea. The goal is to see which approach better strengthens the eye and improves vision.
This trial studies collagen cross-linking, a procedure meant to strengthen a weakened cornea in people with keratoconus. It may help slow the bulging/weakening of the cornea and improve vision, and the study also uses special imaging to check changes over time.
This trial tests two different UV light exposure times (18 minutes vs. 24 minutes) during a corneal crosslinking procedure for people with keratoconus or similar corneal thinning conditions. The goal is to see if the shorter time works as well as the longer one.
This Phase 2 study tests how safe and well a corneal cross-linking device (called PXL-Platinum 330) works for people with corneal ectasia (a thinning/steepening of the cornea). If you qualify, the goal is to help stop or slow further worsening of your cornea shape and improve eye stability.
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