Corneal strengthening treatment for thinning eye shape
Part of Eyes & vision clinical trials.
This Phase 2 study tests how safe and well a corneal cross-linking device (called PXL-Platinum 330) works for people with corneal ectasia (a thinning/steepening of the cornea). If you qualify, the goal is to help stop or slow further worsening of your cornea shape and improve eye stability.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 10 or older
- Your cornea has clear signs of keratoconus, post-surgery ectasia, or pellucid marginal degeneration
- Your cornea topography measurements show it is steep and abnormal (such as Kmax 47.2 D or higher, or I-S difference over 1.5 D)
- Your cornea is not too thin in the thinnest spot (thinnest point over 300 microns) and has enough thickness on tests
- You can hold steady eye gaze during the procedure and testing
- If you wear contacts, you can stop them long enough before screening (soft/scleral 3 days; rigid gas permeable 2 weeks)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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