Clin2
NCT03953014Possibly a fitRecruiting

Genetic study of antidepressant side effects in young people

Obsessive-Compulsive DisorderAnxiety DisordersMajor Depressive DisorderAntidepressant Drug Adverse Reaction

Part of Mental health clinical trials.

This trial studies whether genes (using a saliva sample) can help explain why some young people feel more “disinhibited” after taking antidepressants like SSRIs. If you’ve had depression, anxiety, or OCD and have used an SSRI, your information and genetics may help improve how antidepressants are chosen and monitored.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
120 people
Ages
6 years to 17 years
Study type
Observational

Who can take part

  • Be between 6 and 24 years old
  • Have medical records the study team can review
  • Have a diagnosis of major depression, an anxiety disorder, or OCD
  • Have taken an SSRI (or have a past history of SSRI use)
  • Be willing to provide a saliva sample for genetic testing

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06763081Recruiting
SSRI side effects genetics study

This study looks at why some people have behavioral side effects when taking SSRI antidepressants like Prozac or Zoloft. It hopes to find a genetic reason to help doctors choose safer treatments in the future.

Winnipeg, Manitoba
NCT02431845Recruiting
Study of OCD genes, proteins, and gut microbes

This study looks at genes, blood/brain proteins, and gut microbes in people with obsessive-compulsive disorder (OCD). It may help researchers understand what drives OCD and how treatments could be better tailored in the future.

Seoul
NCT05656469Recruiting
Personalized psychiatry meds using gene test results

This study compares a personalized medication plan based on your genes versus standard dosing for people with depression, anxiety, or psychosis. It may help your clinician choose a safer or more effective dose or medicine by using pharmacogenomics (gene-informed prescribing).

Syracuse, New York
NCT07744490Not yet recruiting
Tracking mental health in children and teens

This study follows children and teens over time to learn how common mental health conditions like depression and anxiety begin. If you have some early signs or a family history, participating could help researchers understand and improve early detection.

Shanghai
NCT04923685Recruiting
Study looks at blood markers linked to childhood trauma and suicide risk

This study checks whether tiny genetic signals in blood (microRNAs) are linked to childhood maltreatment and thoughts or risk of suicide, especially in people with major depression. It may help researchers understand biological clues that could someday guide better care.

Birmingham, Alabama
NCT06853587Recruiting
Genetic test to help pick antidepressant for teens

This study tests whether using a cheek swab DNA test can help choose a better antidepressant for teenagers with anxiety or depression. The goal is to see if this personalized approach leads to fewer side effects and better results.

Calgary, Alberta

Hear when a new Obsessive-Compulsive Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.