Early mitral valve repair versus watchful waiting
Part of Heart & circulation clinical trials.
This trial compares doing mitral valve repair early with closely monitoring symptoms instead, for people who have severe leakage but feel well. It may help determine whether early surgery prevents future heart problems without causing unnecessary risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 18 to 75.
- You feel well from a heart standpoint—no exercise limits or heart-related complaints—confirmed by your cardiologist.
- You have severe “organic” mitral valve leakage (caused by valve damage, not blocked blood flow), confirmed on an echocardiogram.
- Your heart pumping is still strong: ejection fraction over 60% and a certain heart size on ultrasound (LV end-systolic dimension under 45 mm).
- Your heart team believes valve repair is likely (more than 90%).
- You do not have certain exclusions like high lung pressure, atrial fibrillation, very poor kidney function, or being unable to undergo surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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