Comparing two ways to guide mitral valve clip repair
Part of Heart & circulation clinical trials.
This trial tests whether using only ultrasound (echo) to guide a mitral valve clip repair is as good as using ultrasound plus X-ray. The study may help patients with a leaky mitral valve who are not good candidates for open heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a leaky mitral valve (moderate to severe or worse, grade 3+ or 4+).
- Either you have degenerative MR and are at high risk for surgery, or you have functional MR and still leak after 30 days of medical therapy.
- Your mitral valve shape and structure must be suitable for the clip procedure.
- You are willing to participate and complete follow-up visits.
- You have not had a heart attack in the last 12 weeks, and you do not need other heart procedures at the same time.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a clip-based procedure (TEER) to fix a severe leak in the mitral valve for people who have symptoms or heart changes but are at low to medium risk for surgery. The goal is to see if this less invasive option works well and is safe.
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
This study is testing a new assist system to help doctors perform a minimally invasive procedure (MitraClip) that clips the leaky mitral valve without open-heart surgery. It is for people with severe mitral regurgitation who cannot safely have surgery or choose not to.
This trial tests a catheter-based procedure to repair a leaking mitral valve in people who are in severe heart shock and need medication support. The goal is to reduce the valve leak and see if it helps patients stabilize and recover.
This trial studies whether a device called GeminiOne can safely and effectively repair a leaky mitral valve using a catheter-based “clip” technique. It may help patients who have moderate-to-severe or severe valve leakage but are considered too high-risk for open surgery.
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