Breast cancer study after chemotherapy with small underarm node spread
Part of Cancer, Skin clinical trials.
This study looks at whether it’s safe and effective to avoid removing many underarm lymph nodes in some people who, after chemotherapy, still seem to have only tiny (“micro”) cancer deposits in the sentinel lymph node. It may help reduce treatment side effects while keeping cancer control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 18 and 75 years old
- You have invasive (not in-situ) breast cancer
- Your initial scans showed underarm lymph nodes involved (cN+), confirmed by ultrasound and tissue testing
- You finished neoadjuvant chemotherapy, and after that your underarm nodes look negative on exam and ultrasound (cN-)
- No signs of distant spread (M0)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether it's safe to do less extensive lymph node surgery (removing only the sentinel node instead of all lymph nodes) for breast cancer that has spread to lymph nodes, after chemotherapy has shrunk the cancer. The goal is to reduce side effects while still effectively treating the cancer.
This trial tests whether it's safe to skip armpit surgery in people whose breast cancer has responded well to chemotherapy and whose lymph nodes appear cancer-free on ultrasound. It aims to reduce side effects like arm swelling while still controlling the cancer.
This trial tests whether it is safe to skip removing lymph nodes from the armpit when cancer has spread there but has been found by ultrasound. If you have breast cancer that has spread to armpit lymph nodes and are not getting chemotherapy before surgery, this study may be an option.
This study tests whether it is safe and effective to skip surgery on the lymph nodes under the arm in people with early breast cancer that has not spread to those nodes. If you qualify, your breast cancer surgery would be the only surgical treatment you receive.
This study looks at whether some breast cancer patients can safely skip a surgery that removes lymph nodes in the armpit after their initial (pre-surgery) treatment shows the armpit is likely clear. It may reduce surgical side effects if the armpit truly responds well.
This trial compares two ways to treat the underarm lymph nodes in people whose sentinel lymph node still shows limited cancer after chemotherapy and hormone treatment. It may help find which approach controls cancer better with fewer side effects.
Hear when a new Breast cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.