Clin2
NCT06869629Possibly a fitRecruiting

Avoiding armpit lymph node removal in breast cancer

Breast CarcinomaBreast CancerBreast Surgery

Part of Cancer, Skin clinical trials.

This trial tests whether it is safe to skip removing lymph nodes from the armpit when cancer has spread there but has been found by ultrasound. If you have breast cancer that has spread to armpit lymph nodes and are not getting chemotherapy before surgery, this study may be an option.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,380 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with stage 2 or 3 invasive breast cancer.
  • Cancer has been found in one or more armpit lymph nodes, confirmed by a needle biopsy after an ultrasound.
  • You are 18 years or older and can give informed consent.
  • You are not pregnant and have not had breast cancer on the opposite side in the last 5 years.
  • You have not received chemotherapy or other systemic therapy before surgery (a short course of hormone therapy less than 3 months is allowed).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07370571Not yet recruiting
No armpit surgery in early breast cancer

This trial tests whether it is safe to skip armpit (axillary) surgery in people with early breast cancer who have no signs of cancer in their lymph nodes. If you are having breast-conserving surgery and your armpit looks clear on scans, you may not need extra surgery.

NCT05935150Recruiting
Skipping lymph node surgery in early breast cancer

This trial studies whether you can safely avoid a lymph node biopsy in the armpit for early breast cancer when scans and exams look negative. It may reduce surgery-related side effects while still keeping cancer care on track.

Nanjing, Jiangsu
NCT06704945Recruiting· Phase 3
Skipping armpit surgery after good chemo response

This trial tests whether it's safe to skip armpit surgery in people whose breast cancer has responded well to chemotherapy and whose lymph nodes appear cancer-free on ultrasound. It aims to reduce side effects like arm swelling while still controlling the cancer.

Seoul
NCT05939830Recruiting
Skipping axillary lymph node surgery after treatment response

This study looks at whether some breast cancer patients can safely skip a surgery that removes lymph nodes in the armpit after their initial (pre-surgery) treatment shows the armpit is likely clear. It may reduce surgical side effects if the armpit truly responds well.

Nanjing
NCT04019678Recruiting
Breast cancer study after chemotherapy with small underarm node spread

This study looks at whether it’s safe and effective to avoid removing many underarm lymph nodes in some people who, after chemotherapy, still seem to have only tiny (“micro”) cancer deposits in the sentinel lymph node. It may help reduce treatment side effects while keeping cancer control.

Rozzano, MI
NCT06259513Recruiting
Skipping armpit surgery for breast cancer patients

This trial tests whether it's safe to skip armpit surgery in older women with small, low-risk breast cancers. If you qualify, you would have a mastectomy without removing lymph nodes from your armpit.

Singapore

Hear when a new Breast Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.