Tested deep brain–stimulating treatment for hard-to-treat depression
Part of Mental health clinical trials.
This study tests a specialized type of magnetic brain stimulation (spectral TMS) to treat severe major depression when standard treatments haven’t worked. You may be eligible if you’ve tried several antidepressants and other add-on treatments but still have symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 to 65
- Have a confirmed diagnosis of severe major depressive disorder
- Have tried at least 4 antidepressant medications without enough benefit
- Those antidepressant attempts must include at least two different types (classes)
- Have already tried at least two evidence-based “add-on” treatments (but benzodiazepines don’t count)
- Have done psychotherapy that is known to help depression, for enough sessions and time
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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