Removing extra fluid in critically ill ICU patients with overload
Treatments studied
Part of Kidney & urinary clinical trials.
This trial studies a medicine strategy to remove extra fluid from the body in ICU patients who have fluid overload. It aims to see whether controlled fluid removal is safer and better for recovery than usual care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and recently admitted to the ICU
- Your body has at least a 5% fluid overload (based on how much fluid you’ve had in total)
- Your blood pressure and treatments are stable enough (MAP above 50, and noradrenaline dose not higher than 20 mcg/kg/min; lactate under 4)
- Your kidney situation is not severely advanced: no known advanced chronic kidney disease (eGFR below 30 or long-term kidney machine), and you are not already on ongoing dialysis/renal replacement
- You can safely take the study medicines: no allergy to furosemide or sulfonamide antibiotics, no very dangerous bleeding, no major severe electrolyte or liver problems, and consent is possible
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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