Stem cell transplant for hard-to-control Crohn’s disease
Treatments studied
Part of Digestive system clinical trials.
This early-phase study tests whether a stem cell transplant can improve Crohn’s disease in teens and young adults whose disease is active and not responding to standard medicines. It may help some people who are not doing well despite several prior treatments, but it also involves intensive study procedures and safety checks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 13 and 28 years old
- Have confirmed Crohn’s disease that has been present for at least 6 months
- Have active Crohn’s disease now (high inflammation and signs seen by scans/endoscopy/biopsy)
- Have tried several standard Crohn’s medicines (including steroids plus several immunosuppressants/biologics) without enough success or due to side effects
- Be unable to have surgery safely (or be at risk of serious short-bowel problems if surgery is needed)
- Be willing to sign consent and complete extra study visits/tests after counseling
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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