Study of how fat is handled after eating in rare LPL deficiency
Treatments studied
Part of Genetic & congenital, Hormones & metabolism clinical trials.
This study looks at how your body processes fatty acids after meals in people with lipoprotein lipase deficiency (a rare genetic condition). It also compares results to people without the condition, which may help researchers understand metabolism and guide future care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old
- If you are in the LPL deficiency group: you have a known LPL gene mutation and past fasting triglycerides above 5 mmol/L
- If you are in the control group: you should have normal blood sugar test results and low triglycerides
- You must be able and willing to follow the study’s meal and testing schedule and sign consent
- You should not have significant heart disease, liver disease, or kidney disease, or an uncontrolled thyroid problem
- You should not be taking certain diabetes/lipid-affecting medicines (some are allowed if safely stopped, like statins/metformin, depending on your situation)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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