Restarting blood thinners after a head bleed
Treatments studied
Part of Brain & nervous system, Heart & circulation, Injuries & trauma clinical trials.
This Phase 3 trial studies when it is safest to restart a common blood thinner (a DOAC) after a traumatic brain bleed. It may help reduce stroke or clot risk while lowering the chance of another bleeding episode.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a traumatic bleeding in the brain while you were taking a DOAC for atrial fibrillation (AF), a clot, or both
- Your doctor is planning to restart a DOAC, and the timing is uncertain enough to study different restart intervals
- Your risk of future clots or stroke is higher (based on a CHA2DS2-VASc score above 3)
- You likely do not have certain higher-risk bleed features on brain imaging (for example, a large subdural bleed or midline shift)
- You can safely follow the study plan for taking the DOAC and attending required follow-ups
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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