Low-dose steroid timing for newly diagnosed brain tumor surgery
Treatments studied
Part of Cancer clinical trials.
This trial looks at using dexamethasone (a steroid medicine) in a more restricted way for people newly diagnosed with likely glioblastoma who are planned for brain surgery. The goal is to see whether limiting steroid use can still control symptoms while reducing steroid exposure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 90 years old.
- Your MRI/scan shows a suspicious glioblastoma-type tumor in the upper part of the brain (not brainstem), and it can be surgically removed.
- Your scan shows limited swelling effect: midline shift is 3 mm or less.
- Your basic brain function is strong: GCS 14 or higher and NIHSS 3 or lower.
- You have not been taking steroids for more than 1 day before joining, and you don’t need steroid treatment for another condition.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug, FPS-ZM1, given with or without a steroid called dexamethasone, to see if it can reduce brain swelling after surgery for glioblastoma, a type of brain cancer. The goal is to help patients recover better after their tumor is removed.
This study looks at how best to manage blood pressure during lung cancer surgery and whether giving dexamethasone (a steroid medicine) helps patients during the operation and recovery. You might benefit if you’re having longer lung cancer surgery and your heart and other organs are stable enough for the study.
This trial tests how to best use dexamethasone (a steroid) after brain tumor surgery to help recovery and reduce swelling. It looks at different dosing schedules for patients with common brain tumors.
This trial tests whether avoiding steroids and using a study drug called azeliragon can help reduce brain swelling after surgery for a type of brain tumor called high-grade glioma. The goal is to improve recovery and reduce the need for steroids, which can have side effects.
This trial tests whether skipping the steroid dexamethasone around brain tumor surgery is safe and effective for patients with brain metastases. If you have a new brain tumor and a mass elsewhere in your body, you may be able to join.
This trial tests whether a steroid called dexamethasone palmitate can prevent nausea and vomiting after brain surgery. It is for adults having a planned craniotomy under general anesthesia.
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