Study of FPS-ZM1 with or without dexamethasone for brain swelling after glioblastoma surgery
Treatments studied
Part of Cancer clinical trials.
This trial tests a new drug, FPS-ZM1, given with or without a steroid called dexamethasone, to see if it can reduce brain swelling after surgery for glioblastoma, a type of brain cancer. The goal is to help patients recover better after their tumor is removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with glioblastoma or a high-grade glioma, and it can be new or recurrent.
- You are scheduled to have surgery to remove as much of the tumor as possible.
- Your brain MRI shows mild to moderate swelling (less than 10 mm midline shift).
- You have recovered from side effects of previous treatments (except hair loss).
- Your blood counts, liver, kidney, and heart function are within acceptable limits.
- You are willing to use effective birth control or abstain from sexual activity during the study and for 3 months after.
- You are not taking certain medications that could interact with the study drug, and you are able to stop them if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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