Steroid-free approach with study drug for brain tumor surgery recovery
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial tests whether avoiding steroids and using a study drug called azeliragon can help reduce brain swelling after surgery for a type of brain tumor called high-grade glioma. The goal is to improve recovery and reduce the need for steroids, which can have side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a newly diagnosed brain tumor that looks like a high-grade glioma on imaging.
- You are scheduled for surgery to remove more than half of the tumor.
- You have not taken more than 10 mg of dexamethasone (a steroid) and have not used steroids regularly in the past 30 days.
- You are generally able to care for yourself (Karnofsky score of 60 or higher).
- You are not pregnant or breastfeeding, and you agree to use effective contraception if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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