Study brain immune activity in people with mild asthma
Part of Immune system & allergy, Lungs & breathing clinical trials.
This trial studies how immune cells in the brain (called microglia) may be activated in asthma. You may be able to help researchers test whether a specific “immune pathway” differs in certain asthma patients using brain scans and breathing/allergy testing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18–75 years old
- Have a doctor-diagnosed asthma for at least 6 months and it should be mild and well controlled
- Have good lung function at screening (about at least 75% predicted, and at least 70% predicted at baseline)
- Show asthma that reacts to a breathing test (like albuterol improving breathing, or a positive methacholine test)
- Have asthma symptoms triggered by one of these allergens: cats, dust mites, or ragweed (plus a matching positive skin test)
- Be able to safely complete MRI brain scans and avoid “held” medications as instructed before each visit
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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