Transcatheter repair for leaky mitral valve in high-risk adults
Part of Heart & circulation clinical trials.
This pilot study tests a newer catheter-based way to reduce leakage of the mitral valve in people who feel sick from mitral regurgitation but are considered too high-risk for standard surgery. If you fit the valve and heart anatomy needs, the study may help improve symptoms and valve function without open-heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 years or older
- Your mitral valve leak is moderate-severe or severe (at least “3+”), based on heart ultrasound
- You have symptoms from the leak despite the usual heart medications (your care team decides this)
- Your heart team says you are high risk for mitral surgery and are not a good candidate for other approved catheter mitral valve options
- Your mitral valve shape and size are suitable for the study device, and access through a vein from the groin is possible
- You can agree to the consent form and come back for all follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This study tests a new device that replaces a leaking mitral valve without open-heart surgery. It may help people who have severe mitral valve leakage but cannot safely have standard surgery or some other less invasive valve repairs.
This trial studies whether a new catheter-based system can replace a badly leaking mitral valve in people who have symptoms. It may help if you can’t safely get current approved valve treatments or standard surgery.
This study tests a new device called the MRace implant that is designed to repair a leaky mitral valve without open-heart surgery. It may help people with severe leakage who are at high risk for traditional surgery.
This trial tests a new device to fix a leaky mitral valve in people with moderate to severe leakage who are too high-risk for open-heart surgery. It aims to improve heart function and symptoms.
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