Cord cell treatment for severe systemic sclerosis symptoms
Part of Skin clinical trials.
This early-phase study tests whether umbilical cord-derived “cord blood–type” cells can reduce or improve severe systemic sclerosis (a type of hardening/scarring disease of connective tissue). It may help people whose current standard treatments haven’t worked or caused side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have systemic sclerosis confirmed by standard diagnostic criteria
- Your disease is considered severe, such as recent disease with lung or blood-related issues, or higher severity plus organ involvement
- You have tried standard medicine (often methotrexate and/or mycophenolate) for at least 3 months but it didn’t work or caused stopping due to side effects
- You are not eligible for, or do not want, an autologous stem cell transplant (your own stem cells)
- You must be willing and able to give informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether special cells from umbilical cord (UC-MSC) can help treat systemic sclerosis—a disease that causes skin and organ hardening. If you have early systemic sclerosis that hasn't improved enough with standard treatments, this study may offer a new option.
This trial tests whether infusions of donor stem cells from fat tissue can help people with severe systemic sclerosis (a serious autoimmune disease that hardens the skin and can affect internal organs). It is for patients who haven't improved with other treatments or cannot undergo a standard stem cell transplant.
This trial tests whether a special type of stem cells from umbilical cords can help people with scleroderma-related lung disease that is getting worse. You may qualify if your lung function has declined despite current treatments.
This early safety study tests whether an intravenous (through a vein) stem cell product made from donated umbilical cord cells is safe for people with systemic sclerosis. If you join, the goal is to see how your body tolerates the treatment and monitor for side effects.
This trial tests a new cell injection treatment (RY_SW01) for people with systemic sclerosis (a condition causing skin thickening and organ issues). It aims to see if the therapy can improve skin hardening and overall symptoms.
This trial tests whether a special type of immune cell therapy, called CAR T-cells, can help people with severe systemic sclerosis (a disease causing skin and organ hardening) that hasn't improved with standard treatments. The goal is to see if it can stop the disease from getting worse.
Hear when a new Mesenchymal Stem Cells trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.