Donor stem cell infusion for severe scleroderma with lung problems
Part of Heart & circulation, Lungs & breathing, Skin clinical trials.
This trial tests giving stem cells from a healthy donor to people with severe scleroderma that affects their lungs or heart. The goal is to see if these donor stem cells can calm the immune system and ease symptoms when standard treatments have stop working.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have a confirmed diagnosis of systemic sclerosis (scleroderma).
- You have severe lung or heart problems related to scleroderma, such as pulmonary fibrosis or pulmonary hypertension, that haven't improved with standard treatments like cyclophosphamide.
- You are not pregnant, and you agree to use birth control during the study.
- You have a stem cell donor (someone willing to donate their stem cells for you).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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