Stem cell infusion for severe systemic sclerosis
Part of Skin clinical trials.
This trial tests whether infusing stem cells from donated fat tissue can help people with severe systemic sclerosis (an autoimmune disease causing skin thickening and organ damage). The goal is to reduce symptoms and slow disease progression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 70 years old.
- You must have a diagnosis of systemic sclerosis.
- Your disease must be severe, either with recent onset and high skin score, or with significant skin involvement plus major organ problems like lung, kidney, or heart issues.
- You must not be able or willing to have a stem cell transplant using your own cells, or standard treatments have not worked.
- You must agree to use effective birth control if you or your partner could become pregnant.
- You must have health insurance (if applicable).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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Other trials that look related to this one.
This trial tests whether stem cells from umbilical cord blood can help treat systemic sclerosis (scleroderma). The goal is to see if this treatment can improve skin thickening and overall symptoms for people who haven't had success with standard therapies.
This trial tests giving stem cells from a healthy donor to people with severe scleroderma that affects their lungs or heart. The goal is to see if these donor stem cells can calm the immune system and ease symptoms when standard treatments have stop working.
This early-phase study tests whether umbilical cord-derived “cord blood–type” cells can reduce or improve severe systemic sclerosis (a type of hardening/scarring disease of connective tissue). It may help people whose current standard treatments haven’t worked or caused side effects.
This trial tests a new cell injection treatment (RY_SW01) for people with systemic sclerosis (a condition causing skin thickening and organ issues). It aims to see if the therapy can improve skin hardening and overall symptoms.
This Phase 2 study tests whether an “autologous” stem cell transplant—using your own stem cells—can reduce systemic sclerosis disease activity. It is mainly for children, teens, and young adults whose disease did not improve despite standard medicines.
This early safety study tests whether an intravenous (through a vein) stem cell product made from donated umbilical cord cells is safe for people with systemic sclerosis. If you join, the goal is to see how your body tolerates the treatment and monitor for side effects.
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