Study intermittent low oxygen in sleep apnea
Part of Brain & nervous system, Lungs & breathing clinical trials.
This study looks at how repeated episodes of low oxygen during sleep affect the body in people with severe sleep apnea. It may help researchers understand what causes symptoms and long-term risks, which could guide better treatment decisions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe sleep apnea (AHI greater than 30) or belong to the control group with mild sleep apnea (AHI under 5)
- If you are in the control group, your daytime sleepiness score (Epworth) must be greater than 10
- You must not have very high daytime sleepiness (Epworth 18 or higher)
- Your body mass index (BMI) must be 40 or higher
- You should not have certain heart or blood vessel conditions (like high blood pressure, diabetes, prior stroke, or heart disease)
- You should not be using CPAP yet, and you should not take certain medicines (blood pressure meds, statins, diabetes medicines, beta-blockers, or steroid pills)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at how severe sleep apnea breathing patterns relate to body “biomarkers” linked to Alzheimer’s disease, using blood or other measures. It may help researchers understand whether sleep apnea is connected to memory and brain health—and who might benefit most from better sleep care.
This study is looking at a specific sleep-related condition (obstructive sleep apnea) in adults whose blood pressure is not high, and how their blood pressure rhythm changes over the day. If you have sleep apnea, participating could help researchers understand patterns that may affect long-term health.
This trial studies whether mild, controlled low oxygen during sleep can change sleep apnea symptoms and related blood pressure issues. It mainly looks at people with newly diagnosed, untreated sleep apnea and early high blood pressure.
This early-stage study tests a treatment that briefly reduces oxygen during sleep to improve “plasticity,” with the goal of helping people with obstructive or mixed sleep apnea. It also looks at related conditions like high blood pressure and pre-diabetes or cholesterol problems, especially in people who haven’t tried CPAP yet.
This trial tests if brief periods of low oxygen (intermittent hypoxia) can change how immune cells work in people with moderate to severe sleep apnea. It may help understand new ways to reduce inflammation.
This trial studies how temporary low oxygen levels during sleep affect your breathing control. It may help researchers understand and treat sleep apnea better.
Hear when a new Sleep Apnea, Obstructive trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.