Esophageal cancer treatment with chemoradiation plus planned surgery
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests the best way to treat locally advanced squamous cell esophageal cancer: either chemoradiation followed by planned surgery, or monitoring with surgery only if needed. It may help you choose a strategy that controls the cancer while aiming to reduce unnecessary procedures.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed squamous cell cancer of the esophagus that hasn’t spread to distant organs (no M1), and your cancer stage is locally advanced (cT1 N+ or cT2–4a).
- Your care team says your tumor can be removed with surgery (resectable) based on a tumor board review.
- You’re able to do most daily activities (ECOG performance status 0–1).
- You have test results showing your organs (kidneys, liver, heart, lungs, and related hormone systems) can handle combined treatment.
- If you can become pregnant, you must take a pregnancy test that is negative and use highly effective birth control during treatment and for at least 5 months after the last dose; if breastfeeding, you must stop before starting treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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