Clin2
NCT04460521Possibly a fitRecruiting

NAC pills and night splints for carpal tunnel without surgery

Carpal Tunnel SyndromeHand Injuries and DisordersNerve CompressionSplintsCarpal TunnelCarpal Tunnel Release

Treatments studied

Part of Brain & nervous system, Cancer, Injuries & trauma clinical trials.

This trial tests whether N-acetylcysteine (NAC) along with wearing a night wrist splint can improve symptoms of mild to moderate carpal tunnel syndrome. It’s designed for people who want a non-surgical option.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
240 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are at least 18 years old
  • Your carpal tunnel is confirmed as mild to moderate by exam plus a nerve test done within the last year
  • Your symptoms have been going on for at least 6 weeks
  • You have NOT had carpal tunnel surgery on the affected wrist/hand
  • You have NOT had a steroid shot for carpal tunnel in the last 6 months on the affected side
  • You can afford and obtain the required night splint

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05637294Recruiting
Compare night-only versus full-time splinting for carpal tunnel

This study looks at whether wearing a wrist splint only at night works as well as wearing it full-time for carpal tunnel syndrome (CTS). It may help you find the most helpful and practical splint schedule to reduce symptoms.

Helsinki
NCT07614425Recruiting
Surgery for Carpal Tunnel Syndrome Study

This study tests surgical treatment for carpal tunnel syndrome—a condition where a nerve in your wrist gets compressed, causing numbness, tingling, or pain in your hand. You may qualify if you have confirmed carpal tunnel syndrome and conservative treatments like splints haven't helped.

Helsinki
NCT07086846Not yet recruiting
Hand therapy for carpal tunnel in new mothers

This trial compares two gentle hand therapies (myofascial release vs. acupressure) for new mothers with carpal tunnel syndrome. It aims to find which treatment better relieves hand numbness and pain.

Cairo
NCT06208709Recruiting
Carpal tunnel treatment for right hand without surgery

This study tests a new way to treat carpal tunnel syndrome in the right hand without surgery. It may help people with mild to moderate symptoms who have not had recent injections or other treatments.

Tucson, Arizona
NCT07654621Not yet recruiting
Hand therapy plus nerve stimulation for carpal tunnel

This study tests whether combining gentle hand/wrist therapy with a tiny electrical stimulation (needle-like) can improve moderate carpal tunnel syndrome symptoms. It is for adults aged 30–50 who have not had previous carpal tunnel surgery and don't have other health issues affecting the nerves or wrist.

Valencia, Valencia
NCT07359274Not yet recruiting
Mobilization therapy for mild-to-moderate carpal tunnel syndrome

This trial tests two types of hand and wrist exercises to see if they can improve symptoms of carpal tunnel syndrome. It compares nerve gliding exercises with a technique that gently moves the small bones in your wrist to reduce pressure on the nerve.

Kütahya, Yoncalı

Hear when a new Hand Injuries and Disorders trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.