Clin2
NCT04478305Possibly a fitRecruiting

Duavive trial for mood and anxiety in midlife women

MenopauseDepression, AnxietySleepMenopause Related Conditions

Part of Mental health clinical trials.

This Phase 1 study tests Duavive’s effects on mood and anxiety symptoms in women going through perimenopause or early menopause. It may help clarify whether this treatment can reduce depression and/or anxiety symptoms in midlife.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
30 people
Ages
45 years to 60 years
Study type
Interventional

Who can take part

  • You are a woman age 45 to 60
  • You can speak and understand English
  • You are in perimenopause or early menopause (within 10 years after your last period)
  • Your depression or anxiety scores are high (CES-D-10 ≥10 and/or GAD-7 ≥10)
  • You have not had certain cancers (breast, ovarian, or endometrial) and don’t have endometrial overgrowth
  • You don’t have major exclusion conditions like blood clots, active liver disease, or uncontrolled high blood pressure

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07146321Not yet recruiting
Multivitamin supplement for emotional well-being

This study tests whether a daily multivitamin and mineral supplement can improve mental and emotional well-being, especially for people going through perimenopausal symptoms. You would take the supplement daily and track your sleep and activity with a smart ring.

Chicago, Illinois
NCT06962345Recruiting
Testing a new vaginal gel for menopause symptoms

This trial is testing a new non-hormonal gel for vaginal dryness and discomfort after menopause. It aims to see if the gel improves quality of life.

Madrid, Madrid
NCT06975111Recruiting· Phase 2/Phase 3
Improving health during menopause

This trial studies ways to help women during the late menopausal transition. It uses a smartphone app and telehealth visits to track your health and help you feel better.

Aurora, Colorado
NCT06716554Recruiting
Shatavari for menopausal symptoms in women

This study tests whether a natural herb called Shatavari can help with menopausal symptoms like hot flashes, sleep problems, and mood changes. It compares Shatavari to a placebo (a pill with no active ingredient) to see if it is safe and effective.

San Francisco, California
NCT05059626Enrolling by invitation· Phase 4
Test simvastatin and Duavee for endometriosis symptoms

This trial studies whether simvastatin and Duavee can improve endometriosis-related symptoms linked to small blood-vessel problems. You may be eligible if you’re a woman aged 18–45 with confirmed endometriosis and meet safety requirements.

New Haven, Connecticut
NCT06238700Recruiting
Studying allopregnanolone for depression in midlife women

This trial tests whether allopregnanolone, a natural brain chemical, can help depression in women going through menopause. It compares the effects against a placebo to see if it improves mood symptoms.

Boston, Massachusetts

Hear when a new Menopause trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.