Cooling fever in ventilated people with septic shock
Part of Infections clinical trials.
This study tests whether external cooling can safely lower very high fever in people who are on a breathing machine for septic shock. It may help improve outcomes by controlling fever while they are treated for the infection causing their illness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a serious infection that may be community- or hospital-acquired
- A doctor has diagnosed septic shock and you need medicines to raise blood pressure plus lactate is above 2 mmol/L after enough IV fluids
- You are on an invasive breathing machine (mechanical ventilation)
- Your body temperature is above 38.3°C, and it is being treated while you are sedated or receiving IV pain medicine
- You are already receiving IV antibiotics and/or treatment to control the infection source
- A family member or designated person can give consent (or consent is obtained as an emergency inclusion)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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