Metformin to improve immune health in HIV
Treatments studied
Part of Immune system & allergy, Infections clinical trials.
This study tests whether a diabetes drug called metformin can improve the immune system and help keep the HIV virus under control in people who are already doing well on HIV treatment. If you are over 40 and have had a stable viral load for a year, this could be a way to boost your immune health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are HIV positive.
- You have been on a stable HIV treatment (ART) for more than a year, and your viral load has been undetectable for the past 6 months.
- You are older than 40 years.
- You do not have diabetes, and you are not currently being treated for hepatitis C.
- You are not pregnant or planning to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether metformin, a common diabetes drug, can help restore immune system balance in people who have used injection drugs in the past. It includes both people living with HIV and those who are HIV-negative.
This trial tests if empagliflozin, a diabetes medicine, can improve weight and metabolism in people with HIV who take dolutegravir and have a high body mass index (BMI). It may help reduce weight gain linked to HIV treatment.
This study tests whether giving a small protein called IL-15 can help your immune system keep HIV under control after pausing your daily HIV medications. You will stop your meds for a short time under careful monitoring, and the hope is that your body might learn to fight HIV without daily pills.
This study tests whether a drug called letermovir can help keep the immune system calm and healthy in people over 50 with well-controlled HIV. It might reduce immune overactivation that can lead to other health problems.
This study looks at how certain immune cells (NK cells) behave in people who have been on HIV treatment for a long time. It aims to understand why some people's immune systems respond differently, which could help improve future treatments.
This trial tests if a drug can lower inflammation in people with HIV who are on effective treatment. It may help reduce the risk of heart disease and other problems related to chronic inflammation.
Hear when a new HIV/AIDS trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.