NAC to help prevent chemo brain fog in ovarian cancer
Treatments studied
Part of Cancer, Hormones & metabolism, Mental health, Women’s health & pregnancy clinical trials.
This Phase 1/2 study tests whether taking NAC (a supplement medicine) can help prevent or reduce memory and thinking problems after platinum chemotherapy. It targets people with advanced ovarian, fallopian tube, or primary peritoneal cancer who are starting at least six cycles of platinum-based treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are post-menopausal (no periods for 12 months) or have had ovaries removed
- You have stage III or IV epithelial ovarian, fallopian tube, or primary peritoneal cancer
- You can do cancer treatment with your current health status (ECOG 0 to 2) and have expected survival over 1 year
- You are planning or have had cytoreductive surgery, and your treatment includes at least six cycles of platinum-based chemotherapy
- Your blood tests are in acceptable ranges (including blood counts, liver tests, and kidney function)
- You have no history of dementia or major brain conditions, and you do not have cancer in the brain (brain metastases)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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