Clinical trials
Familial Adenomatous Polyposis clinical trials
Below are recruiting familial adenomatous polyposis clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03050268Recruiting
Study of childhood cancer risk in families
This study looks at inherited (family) risk for childhood cancers, including families with early cancers or known cancer risk conditions. It may help researchers understand why some children get cancer and improve future risk detection and care.
Memphis, TennesseeAges Any age - NCT03471403Recruiting
Cold snare removal for duodenal growths in FAP
This trial studies removing small growths in the duodenum (a part of the small intestine) in people with familial adenomatous polyposis (FAP) using a “cold snare” technique. It may help reduce the need for more intensive treatment and make follow-up care safer, but you must meet specific safety and readiness requirements.
Westmead, New South WalesAges 18–99 - NCT04677998Recruiting
Personalized monitoring and treatment plan for stomach polyps
This trial tests a personalized plan for regularly checking and treating stomach and first-part of intestine polyps in people with familial adenomatous polyposis (FAP). It may help by catching problems early and choosing the right intervention at the right time.
Houston, TexasAges 18 years+ - NCT04678011Recruiting
Personalized follow-up to prevent cancer after FAP surgery
This trial studies a tailored plan for surveillance (check-ups) and interventions to find and remove new growths early in people with familial adenomatous polyposis (FAP) after bowel surgery. It may help lower the chance of cancer by closely monitoring and treating polyps when they appear.
Houston, TexasAges 18 years+ - NCT05552755RecruitingPhase 1/Phase 2
Drug trial for FAP to reduce pre-cancer growth
This early-phase trial studies REC-4881 in adults with familial adenomatous polyposis (FAP), a condition that causes many colon/rectum and duodenal polyps. It aims to see whether the treatment can safely help control or shrink polyp growth in people who have had bowel surgery.
Scottsdale, ArizonaAges 18 years+ - NCT05630794RecruitingPhase 1
Test ONC201 to prevent colorectal polyp return in high-risk people
This Phase 1 study tests whether ONC201 is safe and may help prevent colorectal polyps (adenomas) from coming back. You’d also undergo planned colon/rectum camera exams to check for new or changing polyps.
Ann Arbor, MichiganAges 18 years+ - NCT06545526RecruitingPhase 3
Celecoxib and metformin for familial adenomatous polyposis
This trial tests whether a combination of two drugs, celecoxib and metformin, can prevent the growth of polyps in the colon or duodenum (the first part of the small intestine) in people with familial adenomatous polyposis (FAP). FAP is a condition that causes many polyps to form, raising the risk of cancer. If you have FAP, are between 20 and 55, and have at least 5 polyps that are 2mm or larger, this study may be for you.
SeoulAges 20–55 - NCT06578637Recruiting
BHB supplement study for familial adenomatous polyposis
This trial tests whether taking a supplement called beta-hydroxybutyrate (BHB) can help prevent polyps in people with familial adenomatous polyposis (FAP), a condition that causes many polyps in the colon. The study has two parts: one for people who have already had colon surgery, and another for those who still have their colon.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06614738Recruiting
Microbes and environment in polyps after FAP surgery
This study looks at how bacteria and your environment might affect polyp growth in people with familial adenomatous polyposis (FAP) after colon removal. By collecting stool samples and medical information, researchers hope to find ways to reduce polyp risk.
Lyon, FranceAges 18 years+ - NCT06641310Recruiting
Exercise therapy trial for people with familial adenomatous polyposis
This trial tests whether a home-based exercise program can help people with familial adenomatous polyposis (FAP) who have rectal polyps. You may qualify if you have FAP, have not had your rectum removed, have at least 5 rectal polyps larger than 2 mm, and are currently inactive.
Ann Arbor, MichiganAges 18 years+ - NCT06950385RecruitingPhase 3
Testing eRapa medicine for FAP
This trial tests a new medicine called eRapa for people with Familial Adenomatous Polyposis (FAP), a condition that causes many polyps in the colon and raises the risk of cancer. The goal is to see if eRapa can help reduce polyps and improve outcomes.
Arcadia, CaliforniaAges 18 years+ - NCT07199127Recruiting
Studying duodenal polyps in FAP
This study reviews duodenal polyps in people with FAP to improve how they are classified. It uses existing medical records from endoscopies (scope tests) to help doctors better understand and manage polyp growth.
Milan, MIAges 18 years+ - NCT06649825Enrolling by invitation
Vitamin B1 for familial adenomatous polyposis
This trial tests whether taking vitamin B1 can help people with familial adenomatous polyposis (FAP) reduce the number of polyps in their colon or rectum. It is designed for people who still have most of their bowel and have more than 10 polyps.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07726771Recruiting
Pouch endoscopy study in FAP patients
This study uses a tiny camera to look at the pouch created after FAP surgery. It aims to see how well the pouch is doing and if any polyps are growing there.
London, LondonAges 18 years+ - NCT05919264RecruitingPhase 1/Phase 2
FOG-001 for advanced solid tumors with certain gene changes
This trial tests a new drug, FOG-001, alone or with other treatments, for people with advanced solid tumors that have specific changes in the WNT pathway genes. It aims to see if the drug can shrink tumors or slow their growth.
Phoenix, ArizonaAges 18 years+ - NCT06538402Recruiting
Comparing two J-pouch sizes in pouch surgery
This trial compares two different J-pouch sizes (10 cm vs. 15 cm) during surgery for ulcerative colitis or FAP. The goal is to see if one size leads to better outcomes.
AarhusAges 18–60 - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110
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Familial Adenomatous Polyposis trials by city
Studies with a site in or near these metro areas.
Familial Adenomatous Polyposis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for familial adenomatous polyposis?
- Yes. Clin2 currently lists 17 recruiting familial adenomatous polyposis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a familial adenomatous polyposis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a familial adenomatous polyposis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.