Study blood and brain markers in moderate to severe depression
Part of Mental health clinical trials.
This study looks at changes in depression “markers” to understand what treatments help and why. You’ll have non-invasive brain stimulation and scans before and after treatment, over about 8 weeks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 70 years old
- Have major depressive disorder right now, with moderate to severe symptoms (MADRS score over 19)
- Have tried 1 to 4 antidepressant medicines in this current episode without enough improvement
- If you take psychiatric (mental health) medicines, keep the same doses and plan during the scan period
- Be willing and able to get non-invasive brain stimulation, attend visits for about 8 weeks, and give informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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