Testing brain-activity recordings in people with drug-resistant epilepsy
Part of Brain & nervous system clinical trials.
This study looks at brain activity using electrodes placed inside the brain in people with focal, drug-resistant epilepsy before surgery. It may help doctors better map where seizures start and improve planning for treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have focal (localized) epilepsy that does not respond to seizure medicines
- You are scheduled for a pre-surgery workup that includes placing electrodes inside the brain
- The pre-surgery video-EEG assessment is done at the Neurology department at Pitié-Salpêtrière hospital
- You can understand the study and give written consent
- You are not pregnant and not breastfeeding
- You do not have medical reasons that make an intracranial electrode procedure too risky (like serious active infection or certain high-risk health problems)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a new flexible brain sensor to help guide surgery for people with drug-resistant focal epilepsy. It aims to find exactly where seizures start so surgeons can remove that area safely.
This study maps how thinking and memory work by recording brain signals during a presurgical epilepsy workup. It may help doctors better understand drug-resistant focal epilepsy and improve how they plan treatment.
This study looks at special brain wave patterns called "fast-ripples" to help doctors better plan surgery for epilepsy that doesn't get better with medicine. It may improve how surgeons decide where to operate.
This study uses MRI brain scans to see how “epileptic discharges” may affect brain connections in the developing brain. It also scans comparison participants without drug-resistant focal epilepsy to help researchers understand what is different.
This study uses special brain recordings done during electrode implantation to better understand brain activity in people whose symptoms are hard to control with medications. The goal is to help doctors improve how they evaluate and treat certain brain or nerve conditions.
This study tests a new “hybrid” type of electrodes placed inside the brain to better map where seizures start in people with difficult (drug-resistant) focal epilepsy. It may help doctors plan safer and more effective surgery, though it involves an invasive brain monitoring procedure.
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