Brain scan study to learn who responds to spinal cord stimulation
Part of Brain & nervous system, Pain clinical trials.
This trial uses brain imaging to understand which people with long-lasting low back pain are more likely to benefit from spinal cord stimulation (SCS). If you’re being considered for an SCS trial, the scans may help researchers predict response and improve future care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 21 years or older when you sign consent
- Your pain doctor has recommended you try a spinal cord stimulation (SCS) trial for chronic low back pain
- Your low back pain has lasted at least 12 weeks despite other treatments
- You must agree to sign the study consent form approved by an ethics board (IRB)
- You cannot be currently abusing alcohol or illegal drugs
- You must be able to safely have MRI brain/body scans (no MRI-safe restrictions from implants)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is looking at how people with chronic low back pain respond to spinal cord stimulation (a device that sends gentle electrical pulses to the spine to reduce pain). If you already have a spinal cord stimulator, you may help researchers understand how well it works and how it affects your brain.
This trial tests if a spinal cord stimulator with a new way of adjusting electrical settings (called independent current control) can better manage chronic pain in the back, trunk, or limbs. The goal is to find more effective sequences to reduce pain and improve daily life.
This trial tests whether a noninvasive brain stimulation technique called tACS can help reduce chronic low back pain. Participants will have brain scans and receive the treatment over several sessions.
This trial tests a spinal cord stimulator implant to treat chronic low back pain that hasn't improved with standard treatments. The goal is to see if it can reduce pain and improve function in people with a spinal cord injury.
This trial studies whether changing the “stimulation pattern” of spinal cord stimulation can reduce long-lasting pain and improve daily function. You might be a good candidate if you have chronic trunk or leg pain and have already tried multiple pain treatments without enough relief.
This Phase 2 study looks at how spinal cord (or nerve-root) stimulation affects pain signals in the brain and body. You may qualify if you already have a stimulator set to a comfort mode that avoids “tingling” sensations.
Hear when a new Chronic Low Back Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.