Clin2
NCT04660487Possibly a fitRecruiting

How diet carbs affect GVHD after bone marrow transplant

Graft Versus Host Disease

Part of Immune system & allergy clinical trials.

This study looks at whether certain types of gut carbohydrates (called FODMAPs) are linked to graft-versus-host disease (GVHD) after a bone marrow transplant. It may help doctors understand how diet could influence symptoms and outcomes for people with specific blood cancers.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
18 years to 60 years
Study type
Observational

Who can take part

  • You have one of these blood conditions: AML, ALL, MDS, or multiple myeloma (MM)
  • You are being treated with a bone marrow transplant
  • Your transplanted marrow has successfully started working (“engrafted”)
  • You do not have a significant gastrointestinal (stomach/intestine) disease
  • Your age is between 10 and 60 years old
  • You did not take probiotics or prebiotics before joining the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07235501Recruiting
Understanding immune cells after stem cell transplant

This study looks at immune cells in your blood and in tissues affected by chronic graft-versus-host disease (a condition where donor cells attack your body) after a stem cell transplant. By analyzing samples, researchers hope to better understand this condition and improve future treatments.

Duarte, California
NCT03148743Recruiting
Fecal transplant for gut graft-versus-host disease

This study tests whether a fecal transplant (FMT) can help treat gut graft-versus-host disease (gut GVHD), a condition where donated immune cells attack the intestines. If you have gut GVHD and meet age requirements, you may be eligible to receive this treatment in the trial.

Suzhou, Jiangsu
NCT04745221Recruiting
Fecal microbes therapy to help prevent graft-versus-host disease

This trial studies a treatment made from donor gut microbes to help prevent a common complication after a transplant called acute graft-versus-host disease (aGVHD). It may help by improving the balance and variety of gut bacteria during recovery after haploidentical transplant.

Suzhou, Jiangsu
NCT05067595Recruiting· Phase 1
Fecal transplant and fiber for gut graft-versus-host disease

This study tests whether a fecal microbiota transplant (a procedure that puts healthy donor bacteria into your gut) combined with a dietary fiber supplement can help treat gut graft-versus-host disease, a common complication after a stem cell transplant. It may help reduce diarrhea and other gut symptoms.

Seattle, Washington
NCT04373057Recruiting· Phase 1/Phase 2
Prebiotic fiber to prevent gut inflammation after transplant

This early-phase study tests a prebiotic (galacto-oligosaccharide) to see if it can lower or prevent gut inflammation caused by acute graft-versus-host disease (acute GVHD) after a stem cell transplant. If you’re scheduled for an allogeneic transplant, participating may help researchers find safer ways to protect your gut.

Kansas City, Kansas
NCT03819803Recruiting· Phase 3
Fecal transplant for gut graft-versus-host disease

This study tests whether restoring healthy gut bacteria using a fecal microbiota transplant can improve steroid-refractory gut graft-versus-host disease (aGvHD) after stem cell transplant. If your gut symptoms are your first episode and your stool bacteria diversity is low, this trial may be an option worth screening for.

Graz, Styria

Hear when a new Graft Versus Host Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.