Testing safer adaptive deep brain stimulation for Parkinson’s
Part of Brain & nervous system clinical trials.
This trial studies an “adaptive” form of deep brain stimulation (DBS) that adjusts based on brain signals, and is mainly done when the DBS battery (IPG) needs replacement or when people are getting DBS for the first time. It aims to improve safety and effectiveness for Parkinson’s symptoms by using recorded brain activity during treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Parkinson’s disease that is “idiopathic” (not caused by another known condition)
- Your DBS plan involves stimulation in the STN or GPi area, using approved lead types/models
- Your DBS battery (IPG) must be due for replacement within about a year (for people who already have DBS)
- You must be able to understand the study and sign consent, and you may need strong memory and mood screening
- You cannot have certain brain, heart, medication, pregnancy, or safety issues that could block DBS surgery or testing
- Your clinic must be able to record usable brain signals (called LFPs) during testing
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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